Journal Articles

  1. Kalyuzhny AE (2017) What Makes Cells Different from Other Open Access Journals. Cells 6(4): 41.
  2. Hagen J, Zimmerman R, Goetz C, Bonnevier J, Houchins JP, Reagan K, and Kalyuzhny AE (2015) Comparative multi-donor study of IFNγ secretion and expression by human PBMCs using ELISPOT side-by-side with ELISA and Flow Cytometry assays. Cells 4(1): 84-95.
  3. Le Naour M, Lunzer MM, Powers MD, Kalyuzhny AE, Benneyworth MA, Thomas MJ and Portoghese PS. (2014) Putative kappa opioid heteromers as targets for developing analgesics free of adverse effects. J Med Chem. 57(15):6383-92.
  4. Le Naour M, Akgün E, Yekkirala A, Lunzer MM, Powers MD, Kalyuzhny AE and Portoghese PS. (2013) Bivalent ligands that target μ opioid (MOP) and cannabinoid1 (CB1) receptors are potent analgesics devoid of tolerance. J Med Chem. 56(13):5505-13.
  5. Yekkirala AS, Kalyuzhny AE, Portoghese PS. (2013) An immunocytochemical-derived correlate for evaluating the bridging of heteromeric mu-delta opioid protomers by bivalent ligands. ACS Chem Biol. 2013 8(7):1412-6
  6. Yekkirala AS, Lunzer MM, McCurdy CR, Powers MD, Kalyuzhny AE, Roerig SC, Portoghese PS. N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5098-103.
  7. Zhengliang L Wu, Brittany Prather, Cheryl M Ethen, Alex Kalyuzhny and Weiping Jiang (2011) Detection of Specific Glycosaminoglycans and Glycan   Epitopes by in vitro Sulfation using Recombinant Sulfotransferases. Glycobiology.   May;21(5):625-33.
  8. Yekkirala, AS, Kalyuzhny, AE & Portoghese, PS. (2010) Standard Opioid Agonists Activate Heteromeric Opioid Receptors: Evidence for Morphine and [d-Ala2-MePhe4-Glyol5] Enkephalin as Selective μ−δ Agonists. ACS Chem. Neurosci., 1, 146 – 154.
  9. Kalyuzhny A.E.  The Dark Side of the Immunohistochemical Moon: Industry. J Histochem Cytochem. 2009, 57(12):1099-1101.
  10. Ryan C, Giguère S, Hagen J, Hartnett C, Kalyuzhny AE. Effect of age and mitogen on the frequency of interleukin-4 and interferon gamma secreting cells in foals and adult horses as assessed by  an equine-specific ELISPOT assay. Vet Immunol Immunopathol. 2010, 133(1):66-71.
  11. Ma J, Zhang Y, Kalyuzhny AE and Pan ZZ. Emergence of Functional δ-Opioid Receptors Induced by Chronic Morphine.  Mol Pharmacol.2006 Apr; 9(4):1137-45.
  12. Browning KN, Kalyuzhny AE, Travagli RA. Mu-opioid receptor trafficking on inhibitory synapses in the rat brainstem.  J Neurosci. 2004 Aug 18;24(33):9344-52.
  13. Bailey T, Stark S, Grant A, Hartnett C, Tsang M, Kalyuzhny A. A multidonor ELISPOT study of IL-1 beta, IL-2, IL-4, IL-6, IL-13, IFN-gamma and TNF-alpha release by cryopreserved human peripheral blood mononuclear cells.J Immunol Methods. 270(2):171-82, 2002.
  14. Browning KN, Kalyuzhny AE, Travagli RA. Opioid peptides inhibit excitatory but not inhibitory synaptic transmission in the rat dorsal motor nucleus of the vagus. J. Neurosci., 22(8):2998-3004, 2002
  15. Kalyuzhny A, Stark S. A simple method to reduce the background and improve well-to-well reproducibility of staining in ELISPOT assays. J. Immunol. Methods, 257(1-2):93-7, 2001.
  16. Coughlan CM, McManus CM, Sharron M, Gao Z, Murphy D, Jaffer S, Choe W, Chen W, Hesselgesser J, Gaylord H, Kalyuzhny A, Lee VM, Wolf B, Doms RW, Kolson DL. Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Neuroscience 97(3):591-600, 2000.
  17. Kalyuzhny, A.E., Dooema, J., Wessendorf, M.W. Opioid- and GABAa-receptors are co-expressed by neurons in rat brain. NeuroReport 11, (12) 2625-2628, 2000.
  18. Kalyuzhny, A.E., and M.W.Wessendorf.  Serotonergic and GABAergic neurons in the medulla express kappa-opioid receptor immunoreactivity. Neuroscience  90(1), 229-234, 1999.
  19. Kalyuzhny, A.E., and M.W. Wessendorf.  Relationship of mu- and delta-opioid receptors to GABAergic neurons in the central nervous system, including antinociceptive brainstem circuits. J. Comp. Neurol. 392:528-547, 1998.
  20. Kalyuzhny, A.E., and M.W. Wessendorf.  CNS GABA neurons express the µ-opioid receptor: immunocytochemical studies. NeuroReport 8, 3367-3372, 1997.
  21. Kalyuzhny, A. E., Hensleigh, H. C., Arvidsson, U., and R. Elde. Immunocytochemical localization of mu-opioid receptors in follicular cells and preimplantation mouse embryos. Anat. Embryol 195, 451-455, 1997.
  22. Kalyuzhny, A.E., U. Arvidsson, Wei Wu, and M.W. Wessendorf. mu-Opioid and delta-opioid receptors are expressed in brainstem antinociceptive circuits: studies using immunocytochemistry and retrograde tract-tracing. J. Neurosci. 16, 6490-6503, 1996.
  23. Kalyuzhny, A.E., Lee, N.M., Elde, R.  An opioid binding protein (OBCAM) is specifically downregulated by chronic morphine treatment in dorsal root and trigeminal ganglia.  Neuroscience 66, 943-949, 1995.
  24. Kalyuzhny, A.E.  Leitz Multicon in clinical practice: immunology of reproduction. J Scie & Tech Inform, 10 57-60, 1991.
  25. Kalyuzhny, A.E. Loach embryos and what they can tell us about psychotic opioids?  Microscopion  News  (Wild Leitz) N8, 6-7, 1989.
  26. Kalyuzhny,.A.E., Mironova, O.V., Platonov, E.S., Sukhikh G.T. Opioids inhibit development of mouse embryos. Bul Exp Biol & Med  8, 95-98, 1989.
  27. Kalyuzhny  A.E., Cherdantcev V.G. Aggregation of embryonic cells of the  loach Misgurnus  fossilis in vivo and in vitro. Sigma-agonist of opiate  receptors SKF 10.047 as modulator of aggregation. Zh. Evol. Biokhim. Fiziol  24, 808-816, 1989.
  28. Kalyuzhny, A.E., Yarygin, K.N., Sukhikh, G.T. Ornithine decarboxylase activity of loach embryos is regulated by their sigma-receptors Bull Exp Biol Med  7, 97-98, 1989.
  29. Kalyuzhny, A.E., Cherdantcev, V.G., Gromov, S.P. Opiate receptors of embryonic cells as modulators of cell aggregation. Ontogenesis 19,540, 1988.  
  30. Kalyuzhny, A.E., Fitin, A.F., Bakalkin, G.Ya., Cherdantcev, V.G. Do opioids regulate early loach morphogenesis ?  Ontogenesis  19, 539-540, 1988.
  31. Kalyuzhny, A.E., Fitin, A.F.,Gromov, S.P., Bakalkin, G.Ya. Opiate sigma-  binding sites in membranes of oocytes and early loach embryos  Biochimiya (Biochemistry)  52:335-341, 1987.  
  32. Kalyuzhny, A.E., Cherdantcev, V.G., Fitin, A.F., Bakalkin, G.Ya. Opiate sigma-agonist SKF 10.047 affect  development of  early loach embryos Reports USSR Acad Sci  290:974-978, 1986.